A woman in her 30s and an infant are dead after a major collision on eastbound Highway 1 near Chestermere.

Four vehicles were involved in the crash just after 2 p.m. Friday afternoon.

Two other men were taken to hospital, one in his 30s is in critical condition while the other in his 50s is in serious, but stable condition.

The crash has caused serious back-ups on the Trans-Canada Highway, authorities and EMS are asking drivers to take an alternate route.

The highway is closed until further notice.

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